Automated liquid handling robotics


A liquid handling robot is used in automation automated liquid handling robotics chemical or biochemical laboratories. It is a robot that dispenses a selected quantity of reagentsamples or other liquid to a designated container.

Other liquid handling systems are specifically designed for specific experiments, e. An alternative category of liquid handlers mimics the operations of humans, by performing liquid transfers as humans would do. These robots automated liquid handling robotics the cartesian, 3-axis movements implemented in larger workstations, by means of an arm. Anthropomorphic robots better integrate into laboratories designed for manual pipetting operations, since they can strictly reproduce the pipetting procedures adopted by humans.

In some cases like the "Andrew" system shown on the right [1] they can even use the same pipettes and consumables, being based on camera-based vision algorithms like those implemented in modern domotics and robotics developments. Liquid handling robots can be customized using different add-on modules such as centrifugesPCR machinescolony pickersshaking modulesheating modules and others. Some liquid handling robots utilize Acoustic Liquid Handling which uses sound to move liquids without the traditional pipette or syringe.

Control software, either on a connected computer, or integrated into the system itself, allows the user to customize the liquid handling procedures and transfer volumes. From Wikipedia, the free encyclopedia. This article needs automated liquid handling robotics citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.

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Gone are the days when the domain of automated liquid handling was only inhabited by large drug discovery labs using big liquid handling robotics to screen thousands of compounds per day. With developments in both the technology and the associated software used for automated liquid handling, any researcher from any lab can now benefit from the improved accuracy, higher throughput and lower reagent costs that automated liquid handling can provide. With so many options to choose from, and so many different sample dispensing technologies available, such as acoustic, piezoelectric, positive displacement automated liquid handling robotics air displacement dispensing, picking an automated liquid handler that suits your lab and your needs can be difficult.

Over the last 10 years at TTP Labtech, our team of passionate automation engineers, scientists and product designers have been developing both large and small scale automation solutions for use in academia and industry. This blog highlights what we feel are the 5 most important points to consider before purchasing an automated liquid handling solution:.

Make sure the automated liquid handler that you choose is flexible and adaptable. Depending on what your throughput requirements are, you will need to consider whether it can switch between different plate formats.

In addition, you should think about how easy it will be to integrate your liquid handler into any existing automated processes or instruments within your lab. It is worthwhile choosing the right liquid handling systems according to the volume range that will be handled.

The volume range capabilities of liquid handling systems vary and depend on the type of dispensing technology, i. Integration with more than one liquid handler may be an option to cover a wide range of automated liquid handling robotics. Carefully consider the composition and viscosity of the samples that you will be working with.

For example, highly viscous solutions will be difficult to pipette efficiently and effectively with air displacement pipettes, especially at low volumes, rendering some liquid handling systems prone to blockages and breakdowns. If you require to run a automated liquid handling robotics of samples of differing viscosities and surface tensions, then look for a technology that can accommodate this without compromising precision and operational efficiency, e. Working with sub-microliter volumes, cross-contamination may be your major worry.

The automated liquid handling robotics efficient way to do this is to use disposable pipette tips rather than systems that employ tip washing. Not only will this reduce the likelihood of cross contamination but it will also enhance the accuracy and reproducibility of your results.

High automated liquid handling robotics content solutions easily froth up like a milkshake. This can heavily impact on pipetting accuracy and lead to protein precipitation and aggregation. In order to minimise frothing it is advisable to automated liquid handling robotics positive displacement systems rather than air displacement dispensing.

Of course there are many other factors that you should consider before committing to automating your liquid handling processes that will be dependent on the specific assays that you are looking to run. If you would like to discuss your automated liquid handling requirements in detail and discover how TTP Labtech might automated liquid handling robotics able to automated liquid handling robotics you get the most out of your assays, then why not get in touch?

Top tips when choosing the right automated liquid handler for your lab Our blog 06 May, Top tips automated liquid handling robotics choosing the right automated liquid handler for your lab Gone are the days when the domain of automated liquid handling was only inhabited by large drug discovery labs using big liquid handling robotics to screen automated liquid handling robotics of compounds per day.

Points to consider With so many options to choose from, and so many different sample dispensing technologies available, such as acoustic, piezoelectric, positive displacement and air displacement dispensing, picking an automated liquid handler that suits your lab and your needs can be difficult. This blog highlights what we feel are the 5 most important points to consider before purchasing an automated liquid handling solution: Viscosity Carefully consider the composition and viscosity of the samples that you will be working with.

Foaming High protein content solutions easily froth up like a milkshake. Explore our related articles. News Working at the limits of protein crystallography. Our blog Published March 02, News Our IUCr travel grant winner reports back!

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